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Drugs that inhibit CYP2D6 exercise, for instance paroxetine and quinidine, might induce decreased clearance of oxycodone which could lead to a rise in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in a rise in oxycodone Cmax by 11%, AUC by 13%, and t½ elim.Check with your medical doctor or pharmacist if you shoul