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Drugs that inhibit CYP2D6 exercise, for instance paroxetine and quinidine, might induce decreased clearance of oxycodone which could lead to a rise in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in a rise in oxycodone Cmax by 11%, AUC by 13%, and t½ elim.Check with your medical doctor or pharmacist if you shoul
Ritonavir or lopinavir/ritonavir enormously raise plasma concentrations of oxycodone in wholesome human volunteers as a result of inhibition of CYP3A4 and CYP2D6.[58] Rifampicin enormously cuts down plasma concentrations of oxycodone because of robust induction of CYP3A4.An extensive individual record ought to be taken to doc concomitant drugs, lik